C
Explanation:
Choice A - The surface area of a cell affects the rate of diffusion of materials in and out of the cell.
Choice B - A small cell will have a bigger surface area to volume ratio which means that diffusion will be easier and other cell processes will become faster.
Choice C - The volume of the cell affects the rate at which materials are produced.
Choice D - A larger spherical cell will have a low surface area to volume ratio. Therefore, the comparatively large volume of cytoplasm may produce waste products at a rate too high to rely on diffusion through the comparatively small surface area of the cell membrane.