A
Explanation:
Centrifugation is a technique that primarily separates substances based on their density. When a mixture is centrifuged, particles or components with higher density sediment to the bottom of the tube. Choice A is, therefore, correct.
Centrifugation does not separate substances based on their charge. Electrophoresis is a technique that separates particles or molecules based on their charge. Choice B is, therefore, incorrect. Centrifugation does not directly separate substances based on their chemical composition. Other techniques like chromatography may be more suitable for separating substances by chemical composition. Choice C is, therefore, incorrect. Centrifugation does not separate substances based on their colour. Colour differences might be observed during centrifugation, but they are not the basis for separation. Choice D is, therefore, incorrect.